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The Israel Association for Emergency Medicine

ACEP: A Critical Issue in the Management of Adult Patients Presenting to the Emergency Department With Acute Carbon Monoxide Poisoning: Approved by the ACEP Board of Directors January 22, 2025

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From the American College of Emergency Physicians Clinical Policies Subcommittee (Writing Committee) on Carbon Monoxide Poisoning: Richard D. Shih, MD (Writing Committee Chair) Christian A. Tomaszewski, MD, MS, MBA Amy Kaji, MD, MPH, PhD (Methodologist) Deborah B. Diercks, MD, MSc (Committee Chair)

ABSTRACT This clinical policy from the American College of Emergency Physicians addresses a key issue in the evaluation and management of adult patients presenting to the emergency department with acute carbon monoxide poisoning. A writing subcommittee conducted a systematic review of the literature to derive evidence-based recommendations to answer the following clinical question: In emergency department patients diagnosed with acute carbon monoxide poisoning, does hyperbaric oxygen therapy compared with normobaric (room pressure) oxygen therapy improve long-term neurocognitive outcomes? Evidence was graded, and recommendations were made based on the strength of the available data.

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