Abstract 
This manuscript seeks to describe diagnostic considerations in individuals with diabetes mellitus presenting to the ED with abdominal pain. It highlights the importance of early investigation with computerised tomography to differentiate aetiologies that compel early surgical intervention from those which may be treated conservatively.
Key findings
- A major challenge in evaluating abdominal pain in individuals with diabetes mellitus is differentiating those with non-surgical pathology from those causes which mandate urgent surgical intervention.
- Clinical signs, laboratory changes, and electrocardiography may be misleading in individuals with diabetes mellitus and abdominal pain.
- Early computerised axial tomography imaging may be useful in differentiating aetiologies of abdominal pain in individuals with diabetes mellitus presenting to the Emergency Department.
