PODCAST: Vasopressors after ROSC

פוסט זה זמין גם ב: עברית

Jul 23, 2024

Contributor: Travis Barlock MD

Educational Pearls:

  • Recent study assessed outcomes after ROSC with epinephrine vs. norepinephrine

    • Observational multicenter study from 2011-2018

    • 285 patients received epineprhine and 481 received norepinephrine

  • Epinephrine was associated with an increase in all-cause mortality (primary outcome)

    • Odds ratio 2.6; 95%CI 1.4-4.7; P = 0.002

    • Higher cardiovascular mortality (secondary outcome)

    • Higher proportion of unfavorable neurological outcome (secondary outcome)

  • Norepinephrine is the vasopressor of choice in post-cardiac arrest care

References

  1. Bougouin W, Slimani K, Renaudier M, et al. Epinephrine versus norepinephrine in cardiac arrest patients with post-resuscitation shock. Intensive Care Med. 2022;48(3):300-310. doi:10.1007/s00134-021-06608-7

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